Distance of two semitones (one whole tone). The standard step of the major scale.
Root on string 4, fret 0. Interval on string 4, fret 2.
The major 2nd is the foundation of melodic movement in most musical styles. Stepwise scale motion is an alternation of major and minor 2nds. In pop and folk music, second-based motion creates "singable" melodies. In jazz, second-based chord movement (voice leading) is a hallmark of professional arranging.
Sing a major scale up and down — each step includes a 2nd. Learn to distinguish by ear a major 2nd (whole step) from a minor 2nd (half step). On guitar, play two adjacent scale notes on the same string — that is a two-fret interval.
Learn to recognize intervals by ear with the interactive trainer.