Six semitones — exactly in the middle of the octave. One of the most tense intervals, with a strong pull toward resolution.
Root on string 4, fret 0. Interval on string 4, fret 6.
The tritone is a tool of drama. "The Simpsons" theme opens with a tritone. The Black Sabbath riff is built on a tritone. In jazz, tritone substitution allows replacing a dominant with a chord a tritone away. In blues, b5 is the characteristic "dirty" note. In film music, the tritone symbolizes anxiety and danger.
Memorize the opening of "The Simpsons" theme or the "Black Sabbath" riff — that is a tritone. Practice singing exactly 6 semitones from any note. On guitar, a tritone is six frets, convenient for diagonal movement. Try resolving the tritone outward and inward to feel its pull.
Learn to recognize intervals by ear with the interactive trainer.